EIF4A i28

CAT: 0931-T83935Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T83935Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2861994-92-3

Target

Others

Related Pathways

Others

Bioactivity

EIF4A i28, an inhibitor of the eukaryotic initiation factor-4A (eIF4A) with an IC50 of 8.60 μM in an eIF4A ATPase assay, effectively reduces the viability of BJAB Burkitt lymphoma cells, as indicated by an EC50 of 0.46 μM in a CellTiter-Glo (CTG) luminescence cell viability assay. This compound functions as an RNA-competitive, ATP-uncompetitive eIF4A inhibitor.

Smiles

CCCCC1=CC=C(C2=CC=C(C3=NC4=CC=C(C=C4C(C(O)=O)=C3)[N+]([O-])=O)O2)C=C1

Molecular Formula

C24H20N2O5

Molecular Weight

416.43

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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EIF4A i28

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