EIF4E-IN-1

• Target :

  PERK|||Others

• Related Pathways :

  Others|||Apoptosis

• Bioactivity :

  EIF4E-IN-1 (WO2021003194A1, compound Y), is a highly effective inhibitor of eIF4E, a key protein involved in immunosuppression. By targeting immune checkpoint proteins such as PD-1, PD-L1, LAG3, TIM3, and IDO, eIF4E-IN-1 functions to disrupt immune suppression and promote immune release in specific diseases such as cancer and infectious diseases.

• Smiles :

  CN1CCN(CC1)c1c(C#N)c2c(cc1C(F)(F)F)nc(C)n(CCOc1ccc(Cl)cc1-c1cc(C)nc3c(csc13)C(O)=O)c2=O

• Molecular Formula :

  C33H28ClF3N6O4S

• Molecular Weight :

  697.13

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2573979-31-2