EIF4E-IN-4

• Target :

  PERK

• Related Pathways :

  Apoptosis

• Bioactivity :

  EIF4E-IN-4 (Compound 33) is a selective inhibitor of the eukaryotic initiation factor 4E (eIF4E) with a biochemical activity value of 95 nM. It inhibits cap-dependent mRNA translation with an IC50 of 2.5 ?M and is applicable in research on breast cancer, colon cancer, and head and neck cancer.

• Smiles :

  O=C1N=C(NC=2N=C(C=3C=CC(=CC3)P(=O)(O)O)N(C12)CCOC4=CC=C(Cl)C=C4)NC

• Molecular Formula :

  C20H19ClN5O5P

• Molecular Weight :

  475.822

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1373822-39-9