Thio-NAD

• Bioactivity:

  Thio-NAD, a thione-modified derivative of the signaling molecule and enzyme cofactor NAD+, can substitute for NAD+ as a cofactor in alkaline phosphatase (ALP) enzyme activity assays. It is utilized as a substrate in dual-enzyme cycling ELISA for the detection of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike glycoprotein, or surface glycoprotein, and live M. tuberculosis in patient sputum. Thio-NAD is characterized by its absorbance at 405 nm, distinguishing it from other cofactors.

• Smiles:

  NC(=S)C1CCCN(C1)C1OC(COP(O)(=O)OP(O)(=O)OCC2OC(C(O)C2O)n2cnc3c(N)ncnc23)C(O)C1O

• Molecular Formula:

  C21H27N7O13P2S

• Molecular Weight:

  679.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  4090-29-3