Thio-ITP

CAT: 0931-T40359Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0931-T40359Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

27652-34-2

Target

DNA/RNA Synthesis, Others

Related Pathways

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others

Bioactivity

Thio-ITP, also known as 6-Thioinosine 5'-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 μM for RNA polymerase I and 38.0 μM for RNA polymerase II.

Smiles

O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]cnc2=S

Molecular Formula

C10H15N4O13P3S

Molecular Weight

524.23

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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T206548-01	Thio-acridone
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Catalog	Name
HY-115755	Thio-ITP
TRC-M448260-100MG	6-S-Methyl-6-thio-ITP
B7973-.05	ITP
NU-413l	ITPγS
NU-836L	EDA-ITP
BLG-I046-05	ITP-γ-S
MBS5813231	ITP-2
M7ITP001-1	M7-ITP

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