Thio-ITP

• Target:

  DNA/RNA Synthesis|||Others

• Related Pathways:

  DNA Damage/DNA Repair|||Cell Cycle/Checkpoint|||Others

• Bioactivity:

  Thio-ITP, also known as 6-Thioinosine 5'-triphosphate, is a competitive inhibitor of RNA polymerase activity. It exhibits a strong apparent affinity towards the polymerases, with Ki values of 40.9 ?M for RNA polymerase I and 38.0 ?M for RNA polymerase II.

• Smiles:

  O[C@@H]1[C@@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)O[C@H]([C@@H]1O)n1cnc2c1[nH]cnc2=S

• Molecular Formula:

  C10H15N4O13P3S

• Molecular Weight:

  524.23

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  27652-34-2