BChE-IN-20

• Target:

  Cholinesterase (ChE) |||Others

• Related Pathways:

  Neuroscience|||Others

• Bioactivity:

  BChE-IN-20 (compound 7c) is a potent and selective inhibitor of BChE, with IC50 values of 105 nM for eqBChE and 2.3 nM for hBChE. It also inhibits P glycoprotein with an IC50 of 0.27 ?M. BChE-IN-20 serves as a promising template for the design and development of pharmaceutical BChE-selective ligands, including inhibitors and fluorogenic probes.

• Smiles:

  O=C (OC) C1=CN (CCC=2N=C (N=C (NCCCN (CC) CC) C2C1) C=3C=CC=CC3) C (C) C

• Molecular Formula:

  C27H39N5O2

• Molecular Weight:

  465.63

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1428439-79-5