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CL2E-SN38

CAT: 0931-T82710-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T82710-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1639139-65-3
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
CL2E-SN-38 is a structurally stable and highly releasable antibody-drug conjugate (ADC) incorporating SN-38, the active metabolite of Irinotecan and a potent Topoisomerase I inhibitor [1] from the camptothecins class.
Smiles
O=C1N2C(C=3C(C2)=C(CC)C=4C(N3)=CC=C(OC(N(CCN(C(OCC5=CC=C(NC([C@@H](NC([C@H](CC6=CC=CC=C6)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(CNC(=O)C8CCC(CN9C(=O)C=CC9=O)CC8)N=N7)=O)=O)=O)CCCCN)=O)C=C5)=O)C)C)=O)C4)=CC%10=C1COC(=O)[C@@]%10(CC)O
Molecular Formula
C87H116N14O24
Molecular Weight
1741.93
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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