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SN38-COOH

CAT: 0931-T77882-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T77882-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2170118-23-5
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
SN38-COOH, the active metabolite of the topoisomerase I inhibitor irinotecan, is utilized in the synthesis of antibody-drug conjugates (ADCs) . It functions by inhibiting DNA and RNA synthesis [1] [2].
Smiles
O(C(CCC(O)=O)=O)[C@@]1(CC)C2=C(C(=O)N3C(=C2)C=4C(C3)=C(CC)C=5C(N4)=CC=C(O)C5)COC1=O
Molecular Formula
C26H24N2O8
Molecular Weight
492.48
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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