HS-291

• Target :

  ROS Kinase|||Antibacterial

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Microbiology/Virology

• Bioactivity :

  HS-291, a HtpG inhibitor targeting Borrelia burgdorferi (Bb), comprises BX-2819 (high affinity for Bb HtpG), a PEG linker, and Verteporfin (a photoactive toxin) . Upon light activation, HS-291 generates reactive oxygen species that oxidize HtpG and selectively inactivate nearby proteins, leading to the rapid and irreversible inactivation of Bb [1].

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C