DD205-291

• Target :

  PROTACs|||GluR

• Related Pathways :

  PROTAC|||Neuroscience

• Bioactivity :

  DD205-291 is an orally active PROTAC HPK1 degrader with a DC50 of 5.3 nM. It inhibits SLP-76 phosphorylation and induces IL-2 and IFN-?.

• Smiles :

  O=C1NC(=O)CCN1C2=CC(=CC=C2Cl)C(=O)N3CCC(CC3)CC4CCN(C5=NC=C(C=C5)C6=NC7=C(N=C6)NC=C7C=8C=NN(C8)CC(F)(F)F)CC4

• Molecular Formula :

  C38H38ClF3N10O3

• Molecular Weight :

  775.22

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3047066-15-6