ML-291

• Target :

  Others|||PERK|||Apoptosis

• Related Pathways :

  Others|||Apoptosis

• Bioactivity :

  ML291 is a sufonamidebenzamide compound that induces the unfolded protein response (UPR) and overwhelms the adaptive capacity of UPR, resulting in apoptosis in various solid cancer models. It activates the PERK/eIF2a/CHOP apoptotic pathway of UPR and reduces leukemic cell burden [1].

• Smiles :

  [O-][N+](=O)c1ccc(o1)C(=O)Nc1ccc(cc1)S(=O)(=O)N1CCC(Cl)CC1

• Molecular Formula :

  C16H16ClN3O6S

• Molecular Weight :

  413.83

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1523437-16-2