ICMT-IN-18

• Description :

  ICMT-IN-18 (compound 35) is an inhibitor of ICMT (IC50=0.066 μM) [1].

• UNSPSC :

  12352005

• Target :

  ICMT

• Type :

  Reference compound

• Related Pathways :

  GPCR/G Protein

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/icmt-in-18.html

• Solubility :

  10 mM in DMSO

• Smiles :

  N#CC1=CC=CC(NCCC2(C3=CC=CC=C3)CC(C)(C)OCC2)=C1

• Molecular Formula :

  C22H26N2O

• Molecular Weight :

  334.45

• References & Citations :

  [1]Judd WR, et al. Discovery and SAR of methylated tetrahydropyranyl derivatives as inhibitors of isoprenylcysteine carboxyl methyltransferase (ICMT) . J Med Chem. 2011 Jul 28;54 (14) :5031-47.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1313602-81-1]