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ICMT-IN-35

CAT: 0931-T82108-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T82108-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, Transferase
Related Pathways
Metabolism, Others
Bioactivity
ICMT-IN-35 (compound 10n), an ICMT inhibitor with an IC50 value of 0.8 μM, is a FTPA-triazole derivative. It demonstrates cellular uptake by mammalian cells, disrupts K-Ras membrane association, and induces K-Ras mislocalization. Additionally, ICMT-IN-35 exhibits selective cytotoxicity towards ICMT +/+ MEF cells and possesses potent activity against metastatic pancreatic cancer cell lines with an IC 50 of 0.8 μM [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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