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CARM1 degrader-2

CAT: 0931-T79742-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T79742-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Histone Methyltransferase
Related Pathways
Chromatin/Epigenetic
Bioactivity
PROTAC CARM1 degrader-2 (compound 3e), with a DC50 value of 8.8 nM, is a VHL- and proteasome-dependent degrader of co-activator associated arginine methyltransferase (CARM1) . It promotes the degradation of CARM1 and prevents the methylation of its substrates, including poly (A) -binding protein PABP1 and BGR1-associated factor BAF155, consequently inhibiting breast cancer cell migration [1].
Molecular Formula
C72H100N12O7S
Molecular Weight
1277.71
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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