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PDE1-IN-5

CAT: 0931-T79385-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T79385-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others, PDE
Related Pathways
Metabolism, Others
Bioactivity
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 expression induced by LPS. It has demonstrated efficacy in mitigating inflammatory bowel disease (IBD) symptoms in a dextran sodium sulfate (DSS) -induced colitis mouse model, suggesting its potential utility for IBD research [1].
Molecular Formula
C27H29FN4O
Molecular Weight
444.54
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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