PDE1-IN-8

CAT: 0931-MF-0112397-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0112397-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||PDE
Related Pathways
Metabolism|||Others
Bioactivity
PDE1-IN-8 (Compound 3f) acts as an inhibitor of PDE1, with an IC50 of 11 nM. It hinders cAMP and cGMP signaling pathways, impeding the differentiation and proliferation of cells into myofibroblasts, and demonstrates antifibrotic effects in the Bleomycin-induced rat model of pulmonary fibrosis.
Molecular Formula
C17H11Cl2N3OS2
Molecular Weight
408.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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