Immuno modulator-1

• Target :

  Potassium Channel|||Others|||Interleukin|||TNF

• Related Pathways :

  Membrane transporter/Ion channel|||Others|||Immunology/Inflammation|||Apoptosis

• Bioactivity :

  Immuno modulator-1 (compound 22) effectively suppresses the secretion of TNF? and IL-2 in human peripheral blood mononuclear cells (hPBMC), with IC50 values of 4.7 nM and 26 nM, respectively, and exhibits a 20% inhibitory effect on the hERG potassium channel at a concentration of 3 ?M [1].

• Smiles :

  O(CC1=CC=C([C@@H](C)N2CCN(CC2)C3=C(F)C=C(C#N)C=N3)C=C1)C4=C5C(C(=O)N(C5)[C@@H]6C(=O)NC(=O)CC6)=CC=C4

• Molecular Formula :

  C32H31FN6O4

• Molecular Weight :

  582.62

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2757469-20-6