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JAK-IN-26

CAT: 0931-T78189-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T78189-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2417134-93-9
Target
JAK
Related Pathways
Tyrosine Kinase/Adaptors, Stem Cells, JAK/STAT signaling, Chromatin/Epigenetic, Angiogenesis
Bioactivity
JAK-IN-26 (compound 2) is an orally active Janus kinase (JAK) inhibitor with favorable pharmacokinetic properties, demonstrating potency in suppressing IFN-α2B-induced STAT3 phosphorylation in Jurkat cells, with an IC50 value of 17.2 nM [1].
Smiles
O=C(NC1=NC=C(C(=O)CC)C(=C1)NC2=CC=CC(C=3N=CN(N3)C)=C2OC)C4CC4
Molecular Formula
C22H24N6O3
Molecular Weight
420.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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