Products for Research Use Only
RegisterLogin

PF15 TFA

CAT: 0931-T77932-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T77932-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
PROTACs, FLT
Related Pathways
Tyrosine Kinase/Adaptors, PROTAC, Angiogenesis
Bioactivity
PF15 TFA, a PROTAC targeting FLT3 kinase and CRBN, exhibits selective degradation of FLT3-ITD with a DC50 of 76.7 nM. The compound potently suppresses proliferation in FLT3-ITD-positive cells, reduces phosphorylation levels of FLT3 and STAT5, and demonstrates inhibition of tumor growth in murine leukemia models [1].
Molecular Formula
C46H50F3N13O8
Molecular Weight
969.97
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T74259-01PF15
T83742-01SBP1 TFA
T83736-01RTDLDSLRTYTL TFA
T83714-01LAP TFA
T83707-01F9170 TFA
T83702-01E70K TFA
T75801-01TC14012 TFA
T33876L1-01Panomifene TFA
T68166L-01Traxanox TFA
T36201L-01AZD5582 TFA

Alternative Products

CatalogName
HY-143286PF15
HY-143286A-01PF15 (TFA)
MBS5819603PF15 TFA

Popular Products