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ELA-32 (human) TFA

CAT: 0931-T76052-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T76052-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apelin receptor
Related Pathways
GPCR/G Protein
Bioactivity
ELA-32 (human) TFA is a potent apelin receptor agonist with high affinity, demonstrating an IC50 of 0.27 nM and a Kd of 0.51 nM. This compound does not bind to GPR15 or GPR25. It activates the PI3K/AKT signaling pathway, facilitating self-renewal of human embryonic stem cells (hESCs) through cell-cycle progression and protein synthesis. Additionally, ELA-32 (human) TFA enhances the TGFβ pathway, predisposing hESCs towards an endoderm lineage, and promotes angiogenesis in HUVEC cells.
Molecular Formula
C172H290F3N63O41S4
Molecular Weight
4081.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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FSC20579ELA-32 (human)
HY-P2196A-01ELA-32 (human) (TFA)
MBS5817954ELA-32 (human) TFA
007-19[pGlu1]-ELA-32 (Human)
007-30ELA (19-32) / prepro-ELA (41-54) (Human)
H-007-19[pGlu1]-ELA-32 (Human) - Antibody
B-007-25ELA-32 (Human) - Biotin Labeled
T-007-25ELA-32 (Human) - I-125 Labeled
EK-007-19[pGlu1]-ELA-32 (Human) - EIA Kit
G-007-19[pGlu1]-ELA-32 (Human) - Purified IgG Antibody

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