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TAT-cyclo-CLLFVY TFA

CAT: 0931-T75943-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75943-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
HIF/HIF Prolyl-Hydroxylase
Related Pathways
Metabolism, Chromatin/Epigenetic
Bioactivity
TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1α and HIF-1β, with an inhibitory concentration (IC 50) of 1.3 μM [1].
Molecular Formula
C113H189F3N42O26S2
Molecular Weight
2673.1
Shipping Conditions
Ice Packs
Storage Temperature
-20°C