Cyclo (RGDfC) TFA

• Target:

  Integrin

• Related Pathways:

  Cytoskeletal Signaling

• Purity:

  0.9859

• Bioactivity:

  Cyclo (RGDfC) TFA (Cyclo (Arg-Gly-Asp-D-Phe-Cys) TFA) is a cyclic pentapeptide, a cyclic RGD polypeptide with high affinity for ?v?3, which is capable of disrupting cellular integrin interactions. Cyclo (RGDfC) TFA inhibits pluripotent gene expression in embryonic stem cells (ESCs) and inhibits tumorigenic potential of mESCs in vivo. Cyclo (RGDfC) TFA inhibits the tumorigenic potential of mESC. Cyclo (RGDfC) TFA can be used for tumor-related studies.

• Smiles:

  O=C([C@@H](NC(CNC([C@@H](NC([C@@H](NC1=O)CS)=O)CCCNC(N)=N)=O)=O)CC(O)=O)N[C@@H]1CC2=CC=CC=C2.OC(C(F)(F)F)=O

• Molecular Formula:

  C26H35F3N8O9S

• Molecular Weight:

  692.67

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C