Products for Research Use Only

GR231118 TFA

CAT: 0931-T75910-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75910-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Neuropeptide Y Receptor
Related Pathways
Neuroscience, GPCR/G Protein
Bioactivity
GR231118 TFA, a neuropeptide Y C-terminus analogue, acts as a potent, competitive, and relatively selective antagonist at the human neuropeptide YY receptor, exhibiting a pKi of 10.4. It serves as a strong agonist at the human neuropeptide YY4 receptor with a pEC50 of 8.6 and a pKi of 9.6, while demonstrating weak agonistic activity at both human and rat neuropeptide YY2 and YY5 receptors. Additionally, this compound shows high affinity for the mouse neuropeptide YY6 receptor, with a pKi value of 8.8 [1].
Molecular Formula
C112H171F3N34O26
Molecular Weight
2466.76
Shipping Conditions
Ice Packs
Storage Temperature
-20°C