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Huwentoxin-IV TFA

CAT: 0931-T75856-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75856-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Sodium Channel
Related Pathways
Membrane transporter/Ion channel
Bioactivity
Huwentoxin-IV TFA is a potent, selective blocker of sodium channels, specifically inhibiting neuronal Nav1.7, Nav1.2, Nav1.3, and Nav1.4 with IC50 values of 26, 150, 338, and 400 nM, respectively. It preferentially targets the peripheral nerve subtype Nav1.7 by interacting with neurotoxin receptor site 4, demonstrating analgesic effects in animal models of inflammatory and neuropathic pain [1] [2].
Molecular Formula
C176H279F3N52O53S6
Molecular Weight
4220.8
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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