Products for Research Use Only

K41498 TFA

CAT: 0931-T75804-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75804-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CFTR
Related Pathways
Membrane transporter/Ion channel
Bioactivity
K41498 TFA, an analog of antisauvagine-30 (aSvg-30), is a potent and highly selective antagonist of CRF2 receptors, exhibiting K i values of 0.66 nM, 0.62 nM, and 425 nM for human CRF 2α, CRF 2β, and CRF 1 receptors, respectively. This compound effectively inhibits sauvagine-stimulated cAMP accumulation in cells expressing hCRF 2α and hCRF 2β. It is utilized in studies investigating hypotension [1].
Molecular Formula
C164H277F3N48O48
Molecular Weight
3746.22
Shipping Conditions
Ice Packs
Storage Temperature
-20°C