Products for Research Use Only

K41498

CAT: 0931-TP2009Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2009Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
434938-41-7
Target
CRFR
Related Pathways
GPCR/G Protein
Bioactivity
Potent and highly selective CRF2 receptor antagonist (Ki values are 0.66, 0.62 and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively) . Inhibits sauvagine-stimulated cAMP accumulation in hCRF2α- and hCRF2β-expressing cells. In rats in vivo, blocks urocortin-induced hypotension following systemic administration.
Molecular Formula
C162H276N48O46
Molecular Weight
3632.26
Shipping Conditions
Ice Packs
Storage Temperature
-20°C