CALP1 TFA

CAT: 0931-T75791-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T75791-01Size:5 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
CaMK|||Apoptosis|||PDE|||GluR
Related Pathways
Apoptosis|||Metabolism|||Neuroscience
Bioactivity
CALP1 TFA, a calmodulin (CaM) agonist with a dissociation constant (Kd) of 88 µM, selectively binds to the CaM EF-hand/Ca2+-binding site, inhibiting calcium channel opening. This action blocks calcium influx and apoptosis with an IC50 of 44.78 µM, modulates glutamate receptor channel activity, and impedes a store-operated nonselective cation channel. Additionally, CALP1 TFA enhances CaM-dependent phosphodiesterase activity, denoting its multifaceted role in modulating cellular calcium dynamics [1] [2] [3] [4].
Molecular Formula
C42H76F3N9O12
Molecular Weight
956.1
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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