Products for Research Use Only

R18 TFA

CAT: 0931-T75776-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T75776-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Raf
Related Pathways
MAPK
Bioactivity
R18 TFA, a peptide antagonist of 14-3-3, exhibits a dissociation constant (K_D) of 70-90 nM. It efficiently inhibits the interaction between 14-3-3 and its physiological ligand, the kinase Raf-1, thereby significantly impeding the protective effect of 14-3-3 on Raf-1 against phosphatase-induced deactivation [1].
Molecular Formula
C103H158F3N27O31S3
Molecular Weight
2423.73
Shipping Conditions
Ice Packs
Storage Temperature
-20°C