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CAT: 0931-TP2127Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-TP2127Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
211364-78-2
Target
Raf
Related Pathways
MAPK
Bioactivity
Antagonist of 14.3.3 proteins (KD ≈80 nM) . Competitively inhibits 14.3.3-ligand interactions without requiring phosphorylation. Blocks the ability of 14.3.3 to bind to target proteins such as Raf-1, Bad, ASK1 and exoenzyme S.
Smiles
C([C@@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(=O)N1[C@H](C(O)=O)CCC1)CC(C)C)=O)CS)=O)CCSC)=O)CC(N)=O)=O)C)=O)CCC(O)=O)=O)CC(C)C)=O)CC(O)=O)=O)CC(C)C)=O)NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)[C@H]2N(C([C@@H](NC([C@@H](NC([C@H](CC3=CN=CN3)NC(=O)[C@@H]4CCCN4)=O)CS)=O)[C@@H](C)C)=O)CCC2)CCCNC(=N)N)=O)CC(O)=O)=O)CC(C)C)=O)CO)=O)C=5C=6C(NC5)=CC=CC6
Molecular Formula
C101H157N27O29S3
Molecular Weight
2309.69
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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