Cys-McMMAF

CAT: 0931-T74880-01Size: 5 mgDry Ice: NoHazardous: No
CAT#:0931-T74880-01Size:5 mg
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CAS Number
1160590-05-5
Target
Microtubule Associated|||Others
Related Pathways
Cytoskeletal Signaling|||Others
Bioactivity
Cys-McMMAF, the active compound liberated from AlMcMMAF—a humanized anti-5T4 A1 antibody connected to the microtubule-disrupting molecule MMAF through a maleimidocaproyl linker—demonstrates antitumor effectiveness in two mouse tumor models (H1975 and MDA-MB-361-DYT2) [1].
Smiles
[H][C@]1(CCCN1C(=O)C[C@@H](OC)[C@H]([C@@H](C)CC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)CC(SC[C@H](N)C(O)=O)C1=O)C(C)C)[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Molecular Formula
C52H83N7O13S
Molecular Weight
1046.32
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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