McMMAF

• Target:

  Drug-Linker Conjugates for ADC|||Apoptosis|||Microtubule Associated

• Related Pathways:

  Apoptosis|||Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling

• Purity:

  >99.99%

• Bioactivity:

  McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.

• Smiles:

  [C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(CCCCCN3C(=O)C=CC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]

• Molecular Formula:

  C49H76N6O11

• Molecular Weight:

  925.16

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  863971-19-1