McMMAF

CAT: 0931-T16031-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-T16031-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
863971-19-1
Target
Drug-Linker Conjugates for ADC|||Apoptosis|||Microtubule Associated
Related Pathways
Apoptosis|||Antibody-drug Conjugate/ADC Related|||Cytoskeletal Signaling
Purity
>99.99%
Bioactivity
McMMAF is a protective group-conjugated MMAF. MMAF is a potent tubulin polymerization inhibitor.It is a MMAF derivative having a Maleimidocaproyl linker (MC linker), which is ready to conjugate to antibody or other proteins or biopolymers. Mafodotin is a useful agent for make antibody drug conjugate (ADC) for targeted drug delivery.
Smiles
[C@H]([C@H](C(N[C@@H](CC1=CC=CC=C1)C(O)=O)=O)C)(OC)[C@]2(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(CCCCCN3C(=O)C=CC3=O)=O)C)[C@@H](C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC2)[H]
Molecular Formula
C49H76N6O11
Molecular Weight
925.16
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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