USP28-IN-3

• Target:

  DUB

• Related Pathways:

  Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity:

  0.9992

• Bioactivity:

  USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 ?M against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

• Smiles:

  O=C (NC1=CC=C (Cl) C (=C1) C=2C=CC3=C (C2) CCNC3) C4=CC=C (C=C4Cl) S (=O) (=O) C

• Molecular Formula:

  C23H20Cl2N2O3S

• Molecular Weight:

  475.39

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2931509-14-5