USP28-IN-3

• Target :

  DUB

• Related Pathways :

  Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity :

  0.9992

• Bioactivity :

  USP28-IN-3 is a highly selective USP28 inhibitor with an IC50 value of 0.1 ?M against USP28.USP28-IN-3 exhibits anticancer activity and inhibits USP2, USP7, USP8, USP9x, UCHL3, and UCHL5.USP28-IN-3 is cytotoxic to human colorectal and lung squamous carcinoma cells, inhibiting c-cells and c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-neutralizing c-cells through the ubiquitin-proteasome system. -proteasome system to dose-dependently downregulate cellular levels of c-Myc.

• Smiles :

  O=C(NC1=CC=C(Cl)C(=C1)C=2C=CC3=C(C2)CCNC3)C4=CC=C(C=C4Cl)S(=O)(=O)C

• Molecular Formula :

  C23H20Cl2N2O3S

• Molecular Weight :

  475.39

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2931509-14-5