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PROTAC SOS1 degrader-2

CAT: 0931-T74356-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T74356-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2913176-81-3
Target
Others, Ras, PROTACs
Related Pathways
Others, GPCR/G Protein, MAPK, PROTAC
Bioactivity
PROTAC SOS1 degrader-2, a potent degrader of PROTAC SOS1, effectively reduces the expression of pERK and RAS-GTP in a dose-dependent manner. It significantly inhibits tumor growth in vivo [1].
Smiles
C[C@H](NC(=O)[C@@H]1C[C@H](O)CN1C(=O)[C@@H](NC(=O)CCCCCCCCN1CCN(CC1)c1cc(Cl)cc2n(Cc3cc(C)c(F)c(C)c3)c(nc12)N1CC2(CNC2)C1)C(C)(C)C)c1ccc(cc1)-c1scnc1C
Molecular Formula
C57H76ClFN10O4S
Molecular Weight
1051.79
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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