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Nec-3a

CAT: 0931-T73521-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73521-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1504558-72-8
Target
Others, RIP kinase
Related Pathways
Apoptosis, Others, NF-κB
Bioactivity
Nec-3a, an analogue of Necrostatin-3, acts as a RIP1 inhibitor with an inhibition concentration (IC50) of 0.44 μM. This compound successfully impedes the autophosphorylation activity within the RIP1 kinase domain.
Smiles
C(CO)(=O)N1[C@@H]([C@]2(C(=N1)C=3C(CC2)=CC=C(OC)C3)[H])C4=CC(F)=C(OC(F)(F)F)C=C4
Molecular Formula
C21H18F4N2O4
Molecular Weight
438.37
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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