3A-MPLA

• CAS Number :

  1699735-80-2

• Target :

  Others|||TLR

• Related Pathways :

  Immunology/Inflammation|||Others

• Bioactivity :

  Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4) . It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL) -1?, however not as efficient as lipopolysaccharide (LPS) . MPLA improves immune response during bacterial sepsis infection.

• Smiles :

  [NH4+].CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](CO)O[C@H]1OC[C@H]1O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](O)[C@@H]1O

• Molecular Formula :

  C54H106N3O17P

• Molecular Weight :

  1100.42

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C