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3A-MPLA

CAT: 0931-T70268-01Size: 100 mgDry Ice: NoHazardous: No
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CAT#:0931-T70268-01Size:100 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1699735-80-2
Target
Others, TLR
Related Pathways
Immunology/Inflammation, Others
Bioactivity
Monophosphoryl lipid A (MPLA) is a natural agonist for the toll-like receptor-4 (TLR4) . It is useful as an adjuvant in immunization. MPLA is a safe prophylactic agent and has immunotherapeutic applications. It induces tumor necrosis factor and interleukin (IL) -1β, however not as efficient as lipopolysaccharide (LPS) . MPLA improves immune response during bacterial sepsis infection.
Smiles
[NH4+].CCCCCCCCCCCCCC(=O)O[C@H](CCCCCCCCCCC)CC(=O)N[C@@H]1[C@@H](O)[C@H](OP(O)([O-])=O)[C@@H](CO)O[C@H]1OC[C@H]1O[C@H](O)[C@H](NC(=O)C[C@H](O)CCCCCCCCCCC)[C@@H](O)[C@@H]1O
Molecular Formula
C54H106N3O17P
Molecular Weight
1100.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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