TP-050

• CAS Number :

  3085030-47-0

• Target :

  IGluR|||Others

• Related Pathways :

  Membrane transporter/Ion channel|||Others|||Neuroscience

• Bioactivity :

  TP-050 is a potent, selective NMDAR agonist that is orally active, showing EC50 values of 0.51 µM for GluN2A and 9.6 µM for GluN2D. This compound can cross the blood-brain barrier (BBB), enhancing hippocampal long-term (LTP) potentiation and neuronal signal transmission.

• Smiles :

  CC1=CN(C(=O)C2=CC(=NN12)CN3C(=CC(=N3)C(F)F)Cl)[C@H](C)CC#N

• Molecular Formula :

  C16H15ClF2N6O

• Molecular Weight :

  380.78

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C