BT-GSI

CAT: 0931-T73485-01Size: 25 mgDry Ice: NoHazardous: No
CAT#: T73485-01Size: 25 mg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Others|||Gamma-secretase
Related Pathways
Others|||Stem Cells|||Proteases/Proteasome|||Neuroscience
Bioactivity
BT-GSI, a ?-secretase inhibitor (GSI) with bone-targeting capabilities, effectively inhibits Notch signaling. Exhibiting dual action, it possesses both anti-myeloma and anti-resorptive properties, making it a promising candidate for research into multiple myeloma and related bone diseases. Additionally, BT-GSI demonstrates potential in inhibiting tumor growth and the progression of osteolytic disease.
Smiles
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)/C=N/N(C)CCCC(=O)NC(P(=O)(O)O)P(=O)(O)O)NC(=O)OCC1=CC=CC=C1.Br
Molecular Formula
C26H46BrN5O10P2
Molecular Weight
730.52
Shipping Conditions
Cool pack
Storage Temperature
-20°C