BT-GSI

• Target :

  Others|||Gamma-secretase

• Related Pathways :

  Others|||Stem Cells|||Proteases/Proteasome|||Neuroscience

• Bioactivity :

  BT-GSI, a ?-secretase inhibitor (GSI) with bone-targeting capabilities, effectively inhibits Notch signaling. Exhibiting dual action, it possesses both anti-myeloma and anti-resorptive properties, making it a promising candidate for research into multiple myeloma and related bone diseases. Additionally, BT-GSI demonstrates potential in inhibiting tumor growth and the progression of osteolytic disease.

• Smiles :

  CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)/C=N/N(C)CCCC(=O)NC(P(=O)(O)O)P(=O)(O)O)NC(=O)OCC1=CC=CC=C1.Br

• Molecular Formula :

  C26H46BrN5O10P2

• Molecular Weight :

  730.52

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C