RMS-07

• Target :

  Kinesin|||Others

• Related Pathways :

  Cytoskeletal Signaling|||Others

• Bioactivity :

  RMS-07, a covalent inhibitor of Monopolar Spindle Kinase 1 (MPS1/TTK), exhibits a potent inhibitory concentration (IC50) of 13.1 nM. Specifically, it targets a poorly conserved cysteine located in the hinge region of the kinase.

• Smiles :

  C(NC1=C(CC)C=CC=C1CC)(=O)C2=C3N(C=4C(CC3)=CN=C(NC5=C(NC(C=C)=O)C=C(C=C5)N6CCN(C)CC6)N4)C=C2

• Molecular Formula :

  C35H40N8O2

• Molecular Weight :

  604.74

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2645409-78-3