Products for Research Use Only

LZ-07

CAT: 0931-T206708-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206708-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
TNF, Interleukin, PROTACs, IRAK
Related Pathways
Immunology/Inflammation, NF-κB, Apoptosis, PROTAC
Bioactivity
LZ-07 is an IRAK4 PROTAC degrader (DC50 = 1.14 nM), that, upon degradation of IRAK4, significantly inhibits the expression of cytokines such as IL-6, IL-1β, TNF-α, and IL-10. It is applicable in research related to autoimmune diseases.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C