MK-4541

• Target:

  Others|||Reductase|||Androgen Receptor

• Related Pathways:

  Endocrinology/Hormones|||Others|||Metabolism

• Bioactivity:

  MK-4541 is an orally active, selective androgen receptor (AR) modulator that serves as an antagonist to inhibit 5?-reductase. It effectively inhibits proliferation and induces apoptosis in AR-positive prostate cancer cells, significantly reducing the growth of R3327-G prostate tumors in a xenograft mouse model.

• Smiles:

  C[C@@]12[C@@]3 ([C@] ([C@]4 ([C@] (C) (CC3) [C@@H] (NC (OCC (F) (F) F) =O) CC4) [H]) (CC[C@]1 (N (C) C (=O) C=C2) [H]) [H]) [H]

• Molecular Formula:

  C22H31F3N2O3

• Molecular Weight:

  428.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  796885-38-6