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AXL-IN-14

CAT: 0931-T73310-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T73310-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2947506-65-0
Target
TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
AXL-IN-14 is a potent, orally active inhibitor of AXL with an IC50 of 0.8 nM that effectively suppresses Gas6/AXL-mediated cell migration and invasion, reduces the expression of p-AXL and p-AKT proteins, and demonstrates anti-tumor activity [1].
Smiles
CC(C)N1C=C(C(=O)C(=C1)C(=O)NC2=CC(=C(C=C2)OC3=C4C(=NC=C3)NC5=CC=CC=C5O4)F)C6=CC=C(C=C6)F
Molecular Formula
C32H24F2N4O4
Molecular Weight
566.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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