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Axl-IN-19

CAT: 0931-T207381-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T207381-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2870696-46-9
Target
TAM Receptor
Related Pathways
Tyrosine Kinase/Adaptors
Bioactivity
Axl-IN-19 (Compound 68) is a selective inhibitor of AXL, a membrane-bound receptor tyrosine kinase, with an IC50 of 5.3 nM and a cellular KD of 6.8 nM. In rats, Axl-IN-19 demonstrates favorable pharmacokinetic properties, featuring low clearance and moderate bioavailability, and is applicable for cancer research.
Smiles
C(N(C)C)(=O)C1=CC=C(C=2C3=CC(C=4C=C5CC[C@@H](N6C7CC6COC7)CCC5=CC4)=CN=C3NN2)C=C1
Molecular Formula
C31H33N5O2
Molecular Weight
507.63
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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