AXL-IN-13

• CAS Number :

  2376928-82-2

• Target :

  FLT|||PDGFR|||TAM Receptor|||TGF-beta/Smad

• Related Pathways :

  Tyrosine Kinase/Adaptors|||Stem Cells|||Angiogenesis

• Purity :

  0.9995

• Bioactivity :

  AXL-IN-13 is a potent and orally active AXL inhibitor with an IC50 of 1.6 nM and a Kd of 0.26 nM. It exhibits anticancer activity, reverses TGF-?1-induced epithelial-mesenchymal transition (EMT), and inhibits cancer cell migration and invasion.

• Smiles :

  O(C=1C2=C(C=C(OCCCN3CCOCC3)C(OC)=C2)N=CC1)C4=C(F)C=C(NC=5C(C(NC6CCCCC6)=O)=CN(C)N5)C=C4

• Molecular Formula :

  C34H41FN6O5

• Molecular Weight :

  632.72

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C