STAT3-IN-15

• Target:

  STAT|||Others

• Related Pathways:

  Others|||Stem Cells|||JAK/STAT signaling

• Bioactivity:

  STAT3-IN-15, a potent and orally active inhibitor targeting STAT3, effectively combats idiopathic pulmonary fibrosis (IPF) by hindering STAT3 phosphorylation. Additionally, it impedes TGF-?1-induced migration and deformation of epithelial cells and prevents epithelial-mesenchymal transition (EMT), offering a multifaceted approach against IPF.

• Smiles:

  C1CN (CCN1CC2=CC (=C (C=C2F) F) F) C (=O) C3=CC4=CC=CC=C4S3 (=O) =O

• Molecular Formula:

  C20H17F3N2O3S

• Molecular Weight:

  422.42

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C