STAT3-IN-34
- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
STAT3-IN-34
Target :
STATRelated Pathways :
Stem Cells|||JAK/STAT signalingBioactivity :
STAT3-IN-34 (Compound 15E) acts as a STAT3 inhibitor, blocking both the nuclear translocation and the transcriptional regulator activity of STAT3. It effectively inhibits HaCaT cell proliferation with an IC50 value of 0.008 ?M. Additionally, STAT3-IN-34 reduces IL-17A expression and mitigates Imiquimod-induced psoriasis in mouse models.Molecular Formula :
C19H16N2O4SMolecular Weight :
368.41Shipping Conditions :
Cool packStorage Temperature :
-20°C
