STAT3-IN-44

CAT: 0931-MF-0118747-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0118747-01Size:10 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis|||Caspase|||Bcl-2 Family|||STAT
Related Pathways
Apoptosis|||Stem Cells|||Proteases/Proteasome|||JAK/STAT signaling
Bioactivity
STAT3-IN-44 is a potent STAT3 inhibitor with IC50 values of 1.84 ?M (C6 cells) and 4.81 ?M (A549 cells) . It inhibits the phosphorylation of STAT3, downregulates Bcl-2 expression, and upregulates Caspase-3 expression, thereby promoting late-stage apoptosis. STAT3-IN-44 effectively suppresses tumor cell proliferation and migration and is applicable in research on cancers such as glioma and lung cancer.
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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Alternative Products

CatalogName
HY-175010STAT3-IN-44
JH1809444'44'
MBS8560342-01STAT3

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