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STAT3-IN-44

CAT: 0931-T211656-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T211656-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Apoptosis, Caspase, Bcl-2 Family, STAT
Related Pathways
Apoptosis, Stem Cells, Proteases/Proteasome, JAK/STAT signaling
Bioactivity
STAT3-IN-44 is a potent STAT3 inhibitor with IC50 values of 1.84 μM (C6 cells) and 4.81 μM (A549 cells) . It inhibits the phosphorylation of STAT3, downregulates Bcl-2 expression, and upregulates Caspase-3 expression, thereby promoting late-stage apoptosis. STAT3-IN-44 effectively suppresses tumor cell proliferation and migration and is applicable in research on cancers such as glioma and lung cancer.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

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GTR19264006-01STAT3-IN-44
JH1809444'44'
335744-01Stat3

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