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Larotinib mesylate hydrate

CAT: 0931-T72207-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T72207-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2097129-93-4
Target
BTK, Others, IRAK, EGFR
Related Pathways
Others, NF-κB, JAK/STAT signaling, Angiogenesis, Immunology/Inflammation, Tyrosine Kinase/Adaptors
Bioactivity
Larotinib mesylate hydrate is a potent, broad-spectrum, and orally active tyrosine kinase inhibitor (TKI), primarily targeting EGFR with an IC50 value of 0.6 nM.
Smiles
CS(=O)(O)=O.COC(C(OCCCN1C[C@]2([H])[C@](OCCO2)([H])C1)=C3)=CC4=C3C(NC5=CC(Cl)=C(C=C5)F)=NC=N4.CS(=O)(O)=O.O
Molecular Formula
C26H36ClFN4O11S2
Molecular Weight
699.17
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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