P-CAB agent 2 hydrochloride

CAT: 0931-T72181-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T72181-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2209911-80-6

Target

Potassium Channel, Others

Related Pathways

Membrane transporter/Ion channel, Others

Bioactivity

P-CAB agent 2 hydrochloride is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor. It effectively inhibits H+/K+-ATPase activity, with an IC50 value of <100 nM, and targets the hERG potassium channel with an IC50 value of 18.69 μM. Moreover, P-CAB agent 2 hydrochloride demonstrates no acute toxicity and effectively inhibits histamine-induced gastric acid secretion [1].

Smiles

Cl.O=S(=O)(C=1C=CC=C(OCCCOC)C1)N2C=C(C=C2C=3C=CC=CC3F)CNC

Molecular Formula

C22H26ClFN2O4S

Molecular Weight

468.97

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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P-CAB agent 2 hydrochloride

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