P-CAB agent 2

CAT: 0931-T72897-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-T72897-01Size:25 mg
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1978371-23-1
Target
Others|||Potassium Channel
Related Pathways
Membrane transporter/Ion channel|||Others
Bioactivity
P-CAB Agent 2 is a potent, orally active potassium-competitive acid blocker (P-CAB) and gastric acid secretion inhibitor that effectively inhibits H+/K+-ATPase activity, showing an IC50 value of <100 nM. It also demonstrates inhibition of the hERG potassium channel with an IC50 value of 18.69 M, indicating no acute toxicity. P-CAB Agent 2 effectively curbs histamine-induced gastric acid secretion [1].
Smiles
S(=O)(=O)(N1C(=CC(CNC)=C1)C2=C(F)C=CC=C2)C3=CC(OCCCOC)=CC=C3
Molecular Formula
C22H25FN2O4S
Molecular Weight
432.51
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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