Products for Research Use Only
RegisterLogin

CDK8-IN-12

CAT: 0931-T72048-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T72048-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2613307-67-6
Target
PKC, GSK-3, CDK
Related Pathways
PI3K/Akt/mTOR signaling, Stem Cells, Cell Cycle/Checkpoint, Cytoskeletal Signaling, Chromatin/Epigenetic
Purity
0.9983
Bioactivity
CDK8-IN-12 is a selective, potent and orally active inhibitor of CDK8 (Ki: 14 nM) and is an anti-cancer agent. CDK8-IN-12 inhibits GSK-3α, GSK-3β and PCK-θ with Ki of 13 nM, 4 nM and 109 nM respectively. CDK8-IN-12 showed anti-proliferative activity against MV4-11 cells.
Smiles
O=C1C2(CCN(CC2)C=3C(=CN=CC3Cl)C4=CC=5C(O4)=CC=CC5)CCN1
Molecular Formula
C21H20ClN3O2
Molecular Weight
381.86
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T10740-01CDK8-IN-1
T204689-01CDK8-IN-17
T62354-01CDK8-IN-7
T210596-01CDK8-IN-19
T17305-01CDK8-IN-4
T61742-01CDK8-IN-11
T63690-01CDK8-IN-10
T72029-01CDK8-IN-13
T70148-01CDK8-IN-4k
T70098-01CDK8-IN-18

Alternative Products

CatalogName
BA3859-1CDK8-IN-12
521352-01CDK8
BA3104-5CDK8-IN-13
BA3810-10CDK8-IN-1
70R-31732CDK8 antibody
464161CDK8/19i
HY-151463-01CDK8-IN-11
HY-147716CDK8-IN-6
HY-171174-01CDK8-IN-16
HY-162600CDK8-IN-15

Popular Products